DNA construction strategies from graph algorithms
Note: This is a bloggification of these IWBDA 2019 slides on how path-finding tricks used in Google Maps and strategy games can also help build long DNA molecules. Story time! The Edinburgh Genome Foundry, where I worked a few years, is a platform that sells custom synthetic DNA. Customers email long sequences (ATGCTAC..., typically 10,000 nucleotides or longer) which are then synthesized on the robotic setup below, by progressively assembling smaller DNA fragments into bigger ones....